IDENTIFICATION OF SUMOYLATION SITES IN CCDC6, THE FIRST IDENTIFIED RET PARTNER GENE IN PAPILLARY THYROID CARCINOMA, UNCOVERS A MODE OF REGULATING CCDC6 FUNCTION ON CREB1 TRANSCRIPTIONAL ACTIVITY.

CCDC6 was originally identified in chimeric genes as caused by chromosomal translocation involving the RET protooncogene in some thyroid tumors.Recognised as a 65 kDa pro-apoptotic phosphoprotein, CCDC6 has been enrolled as an ATM substrate that contribute to protect genome integrity by modulating PP4c activity in response to genotoxic stress.Recen

The article provides an analysis of the persecution measures against the Roma in Nazi Germany, identifying what measures were taken and, in particular, what tragic consequences they led to on a practical level.The article comparatively analyzes various aspects of the Fixed Blade Tactical persecution of Roma in Germany, and indeed throughout Europe,

Background: Self-medication with antibiotics (SMA) is one of the common factors which precipitate antimicrobial resistance, yet if effective implementations are amended it can be effortlessly controlled.The present Hockey Protective - Gloves - Intermediate study aimed to estimate the prevalence and predictors of SMA in Sudan.Methods: The study adop